lab services
Services for Unit-Dose Nasal Drug Development

Expertise, Tools, and Methodologies for Making Informed Decisions
The development of a successful unit-dose nasal spray or powder is an intricate process that requires a thorough understanding of the interactions between formulation, device, and human usage. Our focused expertise, tools, and methodologies, gained from 25 years of experience with orally inhaled and nasal drug products (OINDPs), provide insight and understanding for making informed decisions to accelerate product success.
Contract test services, performed in our cGMP-compliant lab, evaluate the complex relationships between formulation, device, and human usage. Human actuation studies are carried out with trained testers on patented Ergo™ technology and screening experiments are executed following the controlled Proveris by Design™ approach. Viota® Unit-Dose Software is optimized to control the unique requirements of unit-dose devices resulting in increased accuracy and precision, in a robust format. We work with spray, syringe, pressurized aerosol devices and both liquid and powder formulations for systemic (central nervous system, immune system), nose-to-brain, and local delivery.
Human Actuation Studies
- Orientation (upright and inverted angles)
- Stroke length
- Actuation velocity and acceleration
- Custom methods development activities under Design of Experiment (DoE) protocols
Product Characterization
- Delivered dose
- Droplet size distribution
- Actuation force evaluation
- Spray Pattern (SP), Plume Geometry (PG)
- Plume velocity
- Force to actuate
- Nasal deposition
- Airway deposition
Access current, relevant resources for respiratory drug development & quality control.
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From a Proveris Sales Associate