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White Papers and Posters

Based on twenty years of experience, Proveris Scientific offers a unique blend of technical knowledge and understanding of global regulatory guidelines, incorporating Quality by Design (QbD) in our design of experiments, and effectively assisting our customers. We have authored several white papers and conference posters to support our efforts.

White Papers / Posters Currently Available

Evaluating Spray Characteristics Of Multi-Dose Nasal Spray Devices Across Different Actuator Designs

Poster presented at Respiratory Drug Delivery Asia (RDD) 2018, November 2018.

This study focuses on the effect of different actuators by keeping the pump consistent across water and a drug formulation. Understanding the effects of actuator and formulation on spray pattern can have a significant impact on successful product development.

Reducing Variability in Test Results for OINDPS with Automated Actuation.

Paper discusses the importance of automated actuation for testing inhalation and spray devices to avoid variability introduced by manual methods and explains how Proveris' portfolio of instruments and services can ensure the accuracy and reproducibility of results.

Impact of Actuator Design on Multi-Dose Nasal Spray Characteristics

Poster presented at Respiratory Drug Delivery Tucson (RDD) 2018, April 2018.

Studies the effect device components, such as nozzle/actuators, pump assembly, and dip tube have on drug delivery and performance.

Complete Solutions for pMDI Products: From Development to Quality Control Testing

Paper addresses the challenges encountered in testing pressurized metered dose inhalers, and describes how analytical instrumentation can be used to improve quality and workflow efficiency.

Addressing the challenges in nasal device testing: Evaluation of pump performance

Paper presents solutions to address three main challenges faced by the OINDP industry:

1. Reproducibility of data.
2. Lack of investigative tools to evaluate pump performance during OOS.
3. Increasing productivity while maintaining high quality of data.

Spray pattern: A rapid and sensitive early development tool for respiratory drug products

Paper examines spray pattern against changes in the sump design for pressurized metered dose inhaler (pMDI) products, specifically orifice diameter, orifice length and sump chamber depth parameters.

What is Quality by Design and why should you care?

Paper discusses how a QbD approach is an indispensable tool for successfully developing inhaled and nasal drug products as well as critical to creating effective manufacturing processes for released products.

Understanding the importance and effects of shaking on pMDI performance

Poster presented at Drug Delivery to the Lungs 26.

How critical quality attributes and process variables drive the in-vitro performance of pMDIs: new technologies and methods

Poster presented at Inhalation Asia 2015.

Request Access to White Papers/Posters

Please contact us by filling out the form below if you want to download any of the white papers / posters listed on this page. Someone will respond to you shortly with download instructions.
"Proveris Scientific Corporation provides expert support for nasal developers. They are fast, reliable and are professionals at installing of their equipment and supports in demanding challenges." Dr. Peter Svete, Head of Physical Analytics, Lek Pharmaceuticals d.d.
"Proveris provides insightful and thorough test services. We would recommend working with Proveris. Proveris has great expertise in spray analysis." Elaine Schutte, Chief Development Officer, ProFibrix
"I want to express my sincere gratitude towards Proveris and the service team for being there to make sure our study goes well. The study just completed few minutes ago and thankfully everything went well.......while we conducted SAC study. It was a great display of professionalism by Proveris." ,
"As customary, Proveris's service team provided excellent service and was able to answer my questions." ,
"Thank you for the thorough training on our new equipment. I wish more companies would implement your hands on approach when it comes to training. Thanks again." ,
“We really appreciate the creativity and work conducted at Proveris for their Test Services (Proveris by Design®). Their knowledge, experience, and insight with OINDP’s was very helpful. Thanks to the Proveris team, we have a wonderful solution that we can use for commercial products!” Mic Iwashima, NDS Division, Shin Nippon Biomedical Laboratories, Ltd