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Impact of Actuator Design on Multi Dose Nasal Spray Characteristics

Author: Heli Chauhan, Senior Applications Chemist

Developing a successful multi-dose nasal spray is a challenging and complex process. A number of components and critical parameters need to be precisely controlled to achieve successful dose delivery. Although the properties of the formulation such as viscosity, surface tension have been widely characterized, less has been studied about the effect of device components: nozzle/actuators, pump assembly, and dip tube on drug delivery and performance.

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