Skip to content

products

PMDI COLLECTION SYSTEM

Improve the consistency of your sample collection for delivered dose uniformity (DDU) and aerodynamic particle size distribution (APSD) testing using the unrivaled performance of the Vereo® Automated Actuator

Improper shaking and shake-to-fire timings can cause the delivered dose to vary from 75% to 320% of label claim per actuation. And out-of-specification results for the delivered dose during a single actuation can change the total drug concentration, introducing variability that will impact results.

The Kinaero Cx provides a reliable automated solution where shaking parameters, shake-to-fire timing, actuation parameters, and flow rate can all be tightly controlled for reproducible results. The system’s flexible design simplifies testing by offering a single platform for both DDU and APSD sample collection.

Based on Proven Vereo® Actuator Technology

  • Automated shaking, priming, dose sample collection, and fire-down enables consistent dose delivery for HPLC analysis
  • Robust, proven functionality lets you model human usage of your product, ensuring precise control of important actuation parameters, including force limit, position, velocity, acceleration, stroke length, contact, and end-of-stroke limits
  • An integrated shake axis and software for programming the shake angle, duration, frequency, allows for proper mixing of suspension formulations and tight control of shake-to-fire timing for achieving accurate, reproducible results

Flexible Design Allows for a Fast, Smooth Workflow

  • The unique snap-fit design with back-end adapter to the DUSA tube and the waste collector allows for easy installation and removal for sample prep when performing DDU testing
  • A cascade impactor kit (not shown) makes it easy to setup for APSD testing and to switch between DDU and APSD workflows
  • An on-board sensor (not shown) confirms the inhaler positioning for mating inhalers of different geometries to the sample collection or priming locations (no teaching required).
  • Easy switching between different inhaler types using device holder inserts adapted to various inhaler geometries

Powerful Software Platform Supports Data Storage and Regulatory Compliance

  • Create and manage users with definable permissions (i.e., Administrators, Developers, and Operators)
  • Easily set up a method calling for multiple DUSAs to match your current workflow (e.g., 3 beginning, 4 middle, 3 end of life)
  • Develop and store specific methods to test products that include all necessary actuation parameters and flow conditions for sample collection
  • Open and run saved methods and store data in a local database for easy review of information
  • Create and evaluate products using advanced features such as force/position vs time plots for all actuations to aid in OOS investigations
  • Tools for full regulatory compliance (FDA 21 CFR Part 11)

Resource Library

Access current, relevant resources for respiratory drug development & quality control.

Instrument Support

Ensure uninterrupted operation with on-site and remote support from experienced engineers.

Lab Services

Make informed decisions with study results & consultations with our application scientists.

request a callback

From a Proveris Sales Associate