Proveris designed the Vereo® automated actuator to replicate human usage of orally inhaled and nasal drug products (OINDPs). The actuator provides a central element for conducting required OINDP in vitro tests, which are mandated by the FDA and other regulatory agencies.
Vereo actuators are available as a standalone or can be fully integrated into the SprayVIEW® and Indizo® systems. Each actuator is delivered with two universal device holders. Proveris can also design device specific holders to match the contours of proprietary devices.
Other benefits of Vereo actuators include:
Replicating human use can be accomplished.
As recommended by the FDA, true human actuation can be replicated through the Vereo electromechanical actuator. The actuation parameters can be easily set based on patient population, and can be enhanced through a patented Proveris by Design™ process study.
Choosing your OINDP device through a Quality by Design (QbD) process can be easily achieved through controlled actuation. Performance of the actuator is reproducible and accurate from actuation-to-actuation for true results.
Automated actuation can confirm your spray device selection.
Plug and play.
The actuator easily detects the spray device without additional set-up supplies for accurate stroke length. The universal device holder allows for consistent placement in the actuator. No need for compressed air.
To test a wide range of devices, Vereo actuators are available in several configurations, including:
Vereo actuator SFMDx, for pMDIs
Vereo actuator NSx, for vertically actuated nasal spray pumps
Vereo actuator OSx, for vertically actuated oral spray pumps
Vereo actuator SSx, for side actuated nasal pumps
Vereo actuator DSx, for dual side actuated nasal pumps
"Together with Proveris's instruments and software, the complete solution provides the scalability Aptar Pharma needs to perform robust, high through-put product testing."
Salim Haffar, President, Aptar Pharma
"Proveris Scientific Corporation provides expert support for nasal developers. They are fast, reliable and are professionals at installing of their equipment and supports in demanding challenges."
Dr. Peter Svete, Head of Physical Analytics, Lek Pharmaceuticals d.d.
"Proveris provides insightful and thorough test services. We would recommend working with Proveris. Proveris has great expertise in spray analysis."
Elaine Schutte, Chief Development Officer, ProFibrix
"I want to express my sincere gratitude towards Proveris and the service team for being there to make sure our study goes well. The study just completed few minutes ago and thankfully everything went well.......while we conducted SAC study. It was a great display of professionalism by Proveris."
"As customary, Proveris's service team provided excellent service and was able to answer my questions."
"Thank you for the thorough training on our new equipment. I wish more companies would implement your hands on approach when it comes to training. Thanks again."
“We really appreciate the creativity and work conducted at Proveris for their Test Services (Proveris by Design®). Their knowledge, experience, and insight with OINDP’s was very helpful. Thanks to the Proveris team, we have a wonderful solution that we can use for commercial products!”
Mic Iwashima, NDS Division, Shin Nippon Biomedical Laboratories, Ltd